EU clashes with Pfizer over vaccines price hike after largest contract in history agreed

Pfizer coronavirus vaccine approved for 12 to 15 year olds

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The coronavirus vaccine producers rebuked Emmanuel Macron’s sidekick Clement Beaune’s claim jabs prices will go up because they need to be retooled to work against the latest variants. Mr Beaune said the new price of the Pfizer antidote will reflect an adaptation to the Delta variant.

He told Radio France Internationale: “To have more demanding contracts with products adapted to the variants will — probably, yes — be a little more expensive, not only for the EU, but for all buyers.”

He added: “The vaccine doses that the EU is currently negotiating with Pfizer and other laboratories are not the same as the first generation of vaccines.

“They’re being adapted, as is requested by the contracts under negotiation, to the variants.”

But on Monday, Özlem Türeci, chief medical officer at BioNTech, denied a third booster will need to be adapted to either the Delta or the Beta variants.

The EU has agreed a deal for an additional 900 million doses of the BioNTech/Pfizer vaccine, with the option to purchase another 900 million.

The pharmaceutical company said that this is the “largest supply contract in the history of the pharmaceutical industry.”

The deal is meant to ensure that the EU is able to provide booster shots.

The German biotech firm said that offering a third dose of its established two-shot vaccine remained the best response to concerns over waning immune protection in the face of the highly contagious Delta variant, as worse strains may emerge.

BioNTech said the more than one billion supply tally as per July 21 was up from the 700 million-plus doses it announced in June.

This compares with AstraZeneca saying last month that it and manufacturing partner Serum Institute of India had supplied a billion doses of its vaccine globally.

Based on delivery contracts signed for more than 2.2 billion doses so far, BioNTech said in a statement detailing its second quarter earnings that it expects to accrue 15.9 billion euros in revenue from the vaccine this year, up from a May forecast of 12.4 billion euros.

That includes sales, milestone payments and a share of gross profit in its partners’ territories, BioNTech added.

Pfizer late last month raised its forecast for its share of 2021 vaccine sales to $33.5 billion and said at the time it believes people will need a third dose of the shot.

Pfizer and BioNTech’s decision in early July to seek authorisation for a third dose drew criticism from US health regulators, who said there was not yet enough data to show booster shots are needed.

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US health agencies have since discussed additional doses for people with compromised immune systems, while Germany and France said they would roll out a third dose for the most vulnerable from September.

That jars with a call by the World Health Organisation to use doses instead to jump-start vaccination campaigns in poorer nations that have so far been left behind.

BioNTech Chief Executive Ugur Sahin said that although work was ongoing to adjust the vaccine to variants it was not clear whether yet another version of the pathogen would supplant the now prevalent Delta variant.

“Making a decision at the moment might turn out to be wrong in three or six months if another variant is dominating,” Mr Sahin said during an analyst call.

Mr Tuereci said lab experiments had shown that a third shot of the established product generated neutralising antibodies against a range of strains and that the antibody boost was above the one following a second dose.

Still, the company reiterated plans to start testing a vaccine adjusted to the Delta variant on humans this month, part of a “comprehensive strategy to address variants”.

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